New Unique Nasal Spray creates a physical barrier proven to neutralise and block COVID-19, colds and flu to protect against expected September resurgence

The number of teachers’ working days missed because of sickness absence has soared by 56 per cent in the wake of the Covid-19 pandemic according to the latest workforce census data from the Department for Education.  With teachers having less contact with others through the summer, especially indoors, it’s likely that there will be the usual seasonal resurgence of illnesses like common colds, flu, stomach bugs and COVID-19 when they get back in the classroom.

BioSURE Global the team behind the first CE marked HIV self-test, has launched BioSURE PRO Protective Nasal Spray - proven safe and effective for 6-hours per use – creating an invisible physical barrier that neutralises and blocks viruses and helps prevent infections caused by rotavirus A (sickness and diarrhoea) RSV (common colds), influenzas (flu) and coronaviruses including COVID-19.  The team is urging teachers to start using it before term starts.

This innovative, patented Nasal Spray has a ‘silver bullet’ ingredient - Ethyl Lauroyl Arginate Hydrochloride (ELAH)* - already used in a leading brand of mouthwash that has gained global  popularity in recent years due to its ability to inactivate viruses and bacteria.  The unique action of the spray creates a barrier in the nasopharynx that protects in seconds and lasts for hours, blocking the attachment of airborne viruses.  Scientific evaluations have confirmed that over 99% of the viruses tested were inactivated.

Suitable for daily use, for all aged 12 and over, BioSURE PRO will cost just £9.99 for everyone using the code TEACHER23 online at www.bebiosure.com and can find it at Well Pharmacy and Amazon on promotion in September. It is drug-free and can be reapplied as needed for continuous protection and with 400 sprays per bottle, it means there is 3 months supply if used daily. BioSURE PRO is not a medicine and uses natural and food safe ingredients meaning it is safe for prolonged daily use, with no side effects or risk of long term dependencies.

 BioSure Global CEO Brigette Bard confirms that heading back to school often increases infection rates, and wants to help keep people well and limit disruption in the classroom:  “Absence rates in schools increased last autumn with UK Health Security Authority Data confirming it’s as a result of seasonal flu and other respiratory illnesses.  We have always been passionate about giving people products so they can feel in control and we’ve developed BioSURE PRO to help stop airborne viruses before they even start.  It’s proven effective at blocking the 3 ‘tripledemic’ viruses RSV, flu and COVID-19 but here in the UK we need to look at a behavioural change for people to take action before they catch an infection, rather than reacting when they have symptoms.”

 Sara Stevens, age 45 who works at St Philomena’s School in Hadleigh Road, Frinton says she’s not had a cold since she’s been using the spray:  “All us teachers recognise that the start of term can be fraught with illnesses .. and actually if I’ve ever changed schools I always seem to get more coughs and colds as I’m not used to the germs from the new school!  It’s so important – particularly at the start of a new school year – to be on the ball and part of that is being at my fittest, so this Nasal Spray is a must have certainly for me!”

Dr Abdul Gaffar, lead of the award winning team of scientists that developed the formula stated, “BioSURE PRO’s unique formula contains ELAH (Ethyl Lauroyl Arginate HCL)*, which  prevents the virus from attaching to the nasal passages — essentially stopping the virus before it can reach a dangerous level. When it gets into nasal passages, it starts replicating very fast, and, when it replicates and reaches certain levels, it is able to move to other areas of the body, especially the lungs, where it creates havoc. We interrupt that process.”

[i][1][1]  [2]Clinical studies have demonstrated BioSURE PRO’s ability to stop viruses before they gain entry to the body, by blocking viral attachment to the nasopharynx.  Independently tested against most common flus, colds and COVID-19 delta and omicron variants BioSURE PRO prevented viral replication in cells treated with the spray vs a control group of untreated cells.  Four times more subjects remained infection-free after a 6-day study period with testing against Delta variant specifically.

BioSURE PRO Protective Nasal Spray is now UKCA marked and MHRA registered. It is also available internationally with the award winning formula proving successful in the USA under the Covixyl brand name [3]

For further information about BioSure, BioSURE PRO Nasal Spray or other products in the range, contact:  emma@eyepr.co.uk (Mble: 07710 774531)  kerry@eyepr.co.uk Mble:   07799714006)

NOTE TO EDITORS:  BioSure Global is registered with MHRA and accredited with the EMA

BioSure Global is a UK company that develops, manufactures and distributes world-class medical devices.  The team have decades of experience working with medical devices in global markets, with a unique insight into self-testing. From product development through to market launch, to building strong, credible brands that are suitable for distribution ranging from direct to consumers (D2C), retail, healthcare, governments & NGO channels.  

 The BioSure Team are deeply passionate about the impact it makes by providing the tools to help "you take control of you". We want everyone to be able to make confident, informed choices that are right for them, on their own terms.  We are continuing to increase our international footprint and truly believe in collaboration. 

#BeBioSure

BioSURE PRO Protective Nasal Spray – Ingredient List

[1] https://www.roi-nj.com/2021/08/03/healthcare/nasal-spray-that-fights-covid-19-n-j-company-says-it-has-created-one/

[2] A Randomized, Double-Blind, Multi-Center Study to Evaluate the Efficacy and Safety of Ethyl Lauroyl Arginate Hydrochloride (ELAH) Formulation Versus a Matching Placebo Formulation Administered as a Nasal Spray to Reduce Viral Load From Nasal Area of Subjects with Coronavirus Disease 2019, Salvacion USA Inc, October 2021 (Study no: SLV-CV19-SPRAY).
Evaluation of the Efficacy of ELAH-COVIXYL-V against in vivo transmission of SARS-CoV-2, BioQual Inc., February 2021 (Study no: SALV-20-01A and SALV-20-02).
Demonstration of Effectiveness of a Nasal Spray to Form a Barrier Against Viral Infection, Perfectus BioMed Group, June 2021 (Study no: PB616-001-Phase-1 and 2a).
Demonstration of Effectiveness of a Placebo to Form a Barrier Against Viral Infection, Perfectus BioMed Group, November 2021 (Study no: PB616-002).
Covixyl-V Physicochemical Characterization, Nanotechnology Characterization Laboratory (Study no: NCL202108C).|Covixyl-V Pharmacokinetics, Nanotechnology Characterization Laboratory (Study no: NCL202108D

[3] https://www.cancer.gov/nano/research/ncl/about-0?cid=eb_govdel

*Ethyl Lauroyl Arginate Hydrochloride (ELAH) : food preservative and disinfectant that has been gaining popularity in recent years due to its ability to inactivate viruses and bacteria.

It was first synthesized in 1976 and Spanish pharma company LAMIRSA patented the process in 1995.  Its first commercial use was as a food preservative in the late 1990s and then in a global brand mouthwash in the early 2000’s. It became the first mouthwash approved as a treatment for gingivitis (rather than merely a prevention) due to its effectiveness. The lead researcher won the 2005 Heroes of Chemistry award for the discovery. The same team that developed that product took what they learned in their application and developed the unique formula of BioSURE PRO Protective Nasal Spray.

ELAH is a cationic surfactant that is effective against a broad range of microorganisms, including gram-positive and gram-negative bacteria, enveloped viruses, and fungi.   Cationic simply means ELAH carries a positive charge.  This is important because respiratory viruses are ‘enveloped viruses’ whose outer membrane is negatively charged.[i]  It means the ELAH molecules are attracted to the viruses.

Surfactants break down surface tension and fats (think of how soap works). Once attached to the virus or bacteria, ELAH’s lauric acid tail (more on that later) breaks down the lipid (fatty) coating, which destabilizes and inactivates the microbes.[ii] 

Gram-positive and Gram-negative are two major classes of bacteria and ELAH works a little differently against each. 

Enveloped viruses include almost all respiratory viruses and these are the viruses against which we tested BioSURE PRO.  Coronaviruses, H1N1 influenza, Human Respiratory Syncytial Virus (RSV) and rotoviruses all showed 99.9% or greater reductions when exposed to ELAH in laboratory testing. 

ELAH:  is made up of three components: lauric acid, L-arginine, and ethanol.

The lauric acid provides a long, hydrophobic (water-repellent) tail, while L-arginine provides the hydrophilic (water soluble) head. The ethanol acts as a solvent and helps ELAH mix efficiently into the nasal spray solution. This unique structure allows ELAH to have a dual mechanism of action against microorganisms.

One of the ways ELAH works against bacteria is by disrupting the outer membrane of microorganisms. The lauric acid tail of ELAH penetrates the fatty lipid bilayer of the bacteria’s cell membrane, causing the membrane to become destabilized and break down. This destabilization leads to the death of the microorganism. [iii]

This mechanism is particularly effective against gram-positive bacteria, as they have a thick peptidoglycan layer – made of sugars and amino acids -that is easily disrupted by ELAH.

ELAH works against gram-negative bacteria in a slightly different way, by binding to the microorganism’s surface. The hydrophilic head of ELAH contains a positive charge, which allows it to bind to the negatively charged cell surface of these bacteria. This disrupts the function of membrane-bound enzymes, leading to the death of the microorganism.

ELAH has also been proven to be very effective against “enveloped” viruses, which have a fatty coating (a “lipid bilayer”) that is similar to the cell membrane of bacteria. ELAH’s lauric acid tail pokes holes in that outer layer, destabilizing all of the viral components and inactivating the virus. As noted above, in testing, ELAH reduced viral loads to below the level of detection (greater than 99.999%).

As it acts entirely outside of the cells in our mucous membranes, it is effectively a nasal soap, breaking down the fatty outer layers of microbes, rendering them harmless.  Not all viruses and bacteria are susceptible to ELAH’s wily ways, but those that are happen to be the types of microbes that cause most infections and illnesses. 

ELAH doesn’t interact with our cells, so therefore BioSURE PRO is not a drug.  It is a topical nasal cleanser that gives a very real layer of protection against airborne viruses. Because of its unique structure and mode of action, ELAH truly is a wondrous molecule for keeping us healthy